Ethyl 1-acetyl-1H-indole-3-carboxylate
نویسندگان
چکیده
The title compound, C(13)H(13)NO(3), was synthesized by acetyl-ation of ethyl 1H-indole-3-carboxyl-ate. The aromatic ring system of the mol-ecule is essentially planar, but the saturated ethyl group is also located within this plane and the overall r.m.s. deviation from planarity is only 0.034 Å. Pairs of C-H⋯O inter-actions connect mol-ecules into chains along the diagonal of the unit cell. Mol-ecules also form weakly connected dimers via π⋯π stacking inter-actions of the indole rings with centroid-centroid separations of 3.571 (1) Å. C-H⋯π inter-actions between methyl-ene and methyl groups and the indole and benzene ring complete the directional inter-molecular inter-actions found in the crystal structure.
منابع مشابه
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The title compound, C21H23NSi, was synthesized by Sonogashira-type reaction of 1-ethyl-3-iodo-2-phenyl-1H-indole with tri-methyl-silyl-acetyl-ene. The indole ring system is nearly planar [maximum atomic deviation = 0.0244 (15) Å] and is oriented at a dihedral angle of 51.48 (4)° with respect to the phenyl ring. The supramolecular aggregation is completed by weak C-H⋯π inter-actions of the methy...
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عنوان ژورنال:
دوره 65 شماره
صفحات -
تاریخ انتشار 2009